STATE-OF-THE-ART NANOTECHNOLOGY BASED DRUG DELIVERY STRATEGIES TO COMBAT COVID-19

The emerging Coronavirus Disease-19 (COVID-19) pandemic has had a global impact on all important aspects of our society. As it is known, SARS-Cov-2 can withstand up to 72 h in adverse environmental conditions, which aid its rapid spread. Woefully, an efficacious and approbated vaccine for the SARS-CoV-2 virus remains unavailable, makes problem more frightening presently complicated bestowing forlorn medical care. Nevertheless, clinical research studying several over-the-counter (OTC) drugs approved other indications confront coronavirus. Over past decade, therapeutic nanoparticles have been regarded as felicitous tool efficient persnickety delivery groups (i.e., drugs, vaccines, siRNAs, peptides) site infection. They adequately convey drug encapsulated nanoparticle designated locus without instigating unsought effects. Besides, they acquiesce use non-invasive imaging methods monitor surface infection response treatment. formulated apposite intranasal meritorious method deliver moiety viral diseases affecting lungs. Applying via route surmounted demerits mucosal administration like circumventing enzymatic degradation moiety, upgrading prolonging action drug, etc., thus corroborate exceptional strategy encounter respiratory viruses In this article, we illuminate promising role effective carriers or immunomodulatory agents help combat COVID-19.
 search criteria used were Pubmed, Medscape, Google scholar, etc keywords are coronavirus, nanoformulations, nanoparticles, delivery, etc. articles range from 2012 2020.